GRK3 Products

Antibodies
GRK3 Antibody
GRK3 Antibody
NBP1-90008
Species: Hu, Mouse
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
GRK3 Antibody (497018)
GRK3 Antibody (497018)
MAB4785
Species: Hu
Applications: WB
Host: Mouse Monoclonal
GRK3 Antibody
GRK3 Antibody
NBP1-57568
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
GRK3 Overexpression Lysate (N ...
GRK3 Overexpression Lysate (Native)
NBP2-10488
Applications: WB
Proteins
GRK3 Recombinant Protein
GRK3 Recombinant Protein
H00000157-P01
Species: Hu
Applications: WB, ELISA, PA
GRK3 Partial Recombinant Prot ...
GRK3 Partial Recombinant Protein
H00000157-Q01
Species: Hu
Applications: WB, ELISA, PA
GRK3 Recombinant Protein Anti ...
GRK3 Recombinant Protein Antigen
NBP1-90008PEP
Species: Hu
Applications: AC
RNAi
GRK3 RNAi
GRK3 RNAi
H00000157-R02
Species: Hu

Description

Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonistmediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first are the second essenger-regulated kinases such as c-AMP dependent protein kinase A and protein kinase C. The second are the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase, GRK 1; two forms of beta-adrenergic receptor kinase, GRK 2 (betaARK, betaARK1) and GRK 3 (betaARK2); IT-11 (GRK 4); GRK 5, GRK 6 and GRK 7.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 157
Alternate Names
  • EC 2.7.11.15
  • EC 2.7.11
  • G-protein-coupled receptor kinase 3
  • GRK3Beta-ARK-2
  • BARK2beta-adrenergic receptor kinase 2
  • beta-ARK-2
  • adrenergic, beta, receptor kinase 2

Research Areas for GRK3

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for GRK3

Learn more about PTMs related to GRK3.

Phosphorylation
Acetylation
Methylation
Dephosphorylation
Prenylation
Palmitoylation

Bioinformatics Tool for GRK3

Discover related pathways, diseases and genes to GRK3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related GRK3 Blog Posts

Check out the latest blog posts on GRK3.
"Freeze!" - Arrestin Antibodies Used in New Serotonin Syndrome Study
The beta-arrestin family regulate receptor binding of G-proteins, a group of seven transmembrane receptor proteins which includes the adrenergic, dopamine and serotonin receptors. Recently, arrestin antibodies were used in a study into Serotonin Syndr...    Read more.
Read more GRK3 related blogs.