Gremlin 1 Products

Description

In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.

Bioinformatics

Entrez	26585 Human
Uniprot	NP_037504 Human NP_037504.1 Human O60565 Human O70326 Mouse
Product By Gene ID	26585
Alternate Names	Cell proliferation-inducing gene 2 protein CKTSF1B1gremlin 1, cysteine knot superfamily, homolog Cysteine knot superfamily 1, BMP antagonist 1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) DAN domain family member 2 DAND2GREMLIN Down-regulated in Mos-transformed cells protein DRMMGC126660 gremlin 1 gremlin 1-like protein gremlin gremlin-1 IHG-2 Increased in high glucose protein 2 increased in high glucose-2 proliferation-inducing gene 2

Research Areas for Gremlin 1

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Neuroscience