GRB2 Products

Antibodies
GRB2 Antibody
GRB2 Antibody
AF3846
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Goat Polyclonal
GRB2 Antibody
GRB2 Antibody
NB100-866
Species: Hu, Mu, Rt, Po
Applications: WB, IHC, PEP-ELISA
Host: Goat Polyclonal
GRB2 Antibody (669604) - (SH2 ...
GRB2 Antibody (669604) - (SH2 Domain)
MAB38461
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Lysates
GRB2 Overexpression Lysate (N ...
GRB2 Overexpression Lysate (Native)
NBL1-11326
Applications: WB
Proteins
GRB2 Recombinant Protein
GRB2 Recombinant Protein
H00002885-P01
Species: Hu
Applications: WB, ELISA, PA
GRB2 Partial Recombinant Prot ...
GRB2 Partial Recombinant Protein
H00002885-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
GRB2 RNAi
GRB2 RNAi
H00002885-R02
Species: Hu
Applications: RNAi, RNAi SP
GRB2 RNAi
GRB2 RNAi
H00002885-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The growth factor bound protein 2 (GRB2) is a 25 kDa cytosolic protein that contains one src homology (SH2) domain and two SH3 domains (1). GRB2 associates with Tyrosine phosphorylated EGFRs and PDGFRs via its SH2 domain. GRB2 also plays a crucial role in two separate insulin pathways leading from the insulin receptor to the Ras protein thus affecting mitogenic signaling (2). Additionally GBR2, a bifunctional adaptor protein, recruits Sos for Ras activation and subsequent signal transmission (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 2885
Alternate Names
  • growth factor receptor-bound protein 3
  • Grb3-3
  • epidermal growth factor receptor-binding protein GRB2
  • EGFRBP-GRB2
  • abundant SRC homology
  • SH2/SH3 adapter GRB2
  • ASH
  • Protein Ash
  • MSTP084
  • Adapter protein GRB2
  • MST084
  • NCKAP2
  • HT027
  • growth factor receptor-bound protein 2

Research Areas for GRB2

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Breast Cancer
Cancer
Extracellular Matrix
Signal Transduction

Bioinformatics Tool for GRB2

Discover related pathways, diseases and genes to GRB2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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