Granzyme K Products

Antibodies
Granzyme K Antibody
Granzyme K Antibody
NBP2-49387
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Granzyme K Antibody
Granzyme K Antibody
NBP1-69353
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Granzyme K Antibody
Granzyme K Antibody
NBP1-69548
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
Granzyme K Overexpression Lys ...
Granzyme K Overexpression Lysate (...
H00003003-T01
Species: Hu
Applications: WB
Granzyme K Overexpression Lys ...
Granzyme K Overexpression Lysate (...
NBL1-11419
Applications: WB
Proteins
Recombinant Human Granzyme K ...
Recombinant Human Granzyme K Protein
H00003003-P01
Species: Hu
Applications: WB, ELISA, PA
Granzyme K Recombinant Protei ...
Granzyme K Recombinant Protein Ant...
NBP2-49387PEP
Species: Hu
Applications: AC
Recombinant Human Granzyme K ...
Recombinant Human Granzyme K Protein
NBP2-23087
Species: Hu
Applications: PAGE
RNAi
Granzyme K RNAi
Granzyme K RNAi
H00003003-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The granzyme family of proteins belong to the larger peptidase S1 family. Granzyme A and granzyme B are serine proteases that facilitate apoptotic signaling in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Within the granules of activated CTLs, granzyme A and B are processed and converted to their active forms by the lysosomal cysteine protease cathepsin C. Once cleaved, these active proteases target distinct substrates for proteolysis and, thereby, mediate apoptosis through two different pathways. Granzyme H localizes to cytoplasmic granules of cytolytic T lymphocytes and is important for target cell lysis in cell-mediated immune responses. Granzyme K (GMZK), also designated granzyme-3 or NK-tryptase-2 (NK-TRYP-2), contains one peptidase S1 domain. Granzyme K is a serine protease localizing to the granules of natural killer cells and cytotoxic T lymphocytes. It is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 3003
Alternate Names
  • EC 3.4.21.4
  • granzyme 3
  • EC 3.4.21
  • fragmentin-3
  • Granzyme-3
  • PRSS
  • Fragmentin-3
  • NK-tryptase-2
  • EC 3.4.21.-
  • NK-Tryp-2
  • tryptase II
  • granzyme K (serine protease, granzyme 3; tryptase II)
  • TRYP2granzyme-3
  • granzyme K
  • granzyme K (granzyme 3; tryptase II)

PTMs for Granzyme K

Learn more about PTMs related to Granzyme K.

Cleavage

Bioinformatics Tool for Granzyme K

Discover related pathways, diseases and genes to Granzyme K. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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