GPR37 Products

Antibodies
GPR37 Antibody (436923)
GPR37 Antibody (436923)
MAB4450
Species: Hu
Applications: ICFlow
Host: Mouse Monoclonal
GPR37 Antibody
GPR37 Antibody
NBP2-49540
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
GPR37 Antibody
GPR37 Antibody
NBP1-02361
Species: Hu, Primate, Monkey
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
GPR37 Recombinant Protein
GPR37 Recombinant Protein
H00002861-P02
Species: Hu
Applications: WB, ELISA, PA
GPR37 Recombinant Protein Ant ...
GPR37 Recombinant Protein Antigen
NBP2-49540PEP
Species: Hu
Applications: AC
GPR37 Recombinant Protein
GPR37 Recombinant Protein
H00002861-G01
Species: Hu
RNAi
GPR37 RNAi
GPR37 RNAi
H00002861-R02
Species: Hu

Description

GPR37 is an Orphan-A GPCR with an unknown ligand. GPR37 was recently identified as the PAEL receptor, a Parkin substrate involved in autosomal recessive juvenile Parkinson's (PDJ) disease. The PAEL receptor becomes unfolded, insoluble, and ubiquitinated when overexpressed, leading to unfolded protein-induced cell death. When the PAEL receptor is ubiquitinated by Parkin, it gets degraded, resulting in the suppression of cell death. The insoluble form of the PAEL receptor accumulates in the brains of PDJ patients and may cause selective neuronal death. GPR37 expression has been reported in brain, liver, and placenta. ESTs have been isolated from brain, embryo, eye, fetal lung/testis/Bcell, gallbladder, heart, liver, liver/spleen, melanocyte/uterus/fetal heart, nerve, placenta, testis, tonsil, and vessel libraries.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 2861
Alternate Names
  • probable G-protein coupled receptor 37
  • hET(B)R-LP
  • Parkin-associated endothelin receptor-like receptor
  • EDNRBL
  • PAELRETBR-LP-1
  • Endothelin B receptor-like protein 1
  • G protein-coupled receptor 37 (endothelin receptor type B-like)

Research Areas for GPR37

Find related products by research area and learn more about each of the different research areas below.

GPCR

PTMs for GPR37

Learn more about PTMs related to GPR37.

Phosphorylation
Methylation
Ubiquitination

Bioinformatics Tool for GPR37

Discover related pathways, diseases and genes to GPR37. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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