GPR17 Products

Antibodies
GPR17 Antibody
GPR17 Antibody
NLS4229
Species: Hu, Primate
Applications: IHC-P, ICC
Host: Rabbit Polyclonal
GPR17 Antibody
GPR17 Antibody
NBP1-51988
Species: Hu, Mu, Rt
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
GPR17 Antibody
GPR17 Antibody
NBP1-87531
Species: Hu, Mouse, Rat
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
GPR17 Overexpression Lysate ( ...
GPR17 Overexpression Lysate (Native)
NBP2-10474
Applications: WB
Proteins
GPR17 Recombinant Protein
GPR17 Recombinant Protein
H00002840-P01
Species: Hu
Applications: WB, ELISA, PA
GPR17 Recombinant Protein Ant ...
GPR17 Recombinant Protein Antigen
NBP1-87531PEP
Species: Hu
Applications: AC
GPR17 Recombinant Protein
GPR17 Recombinant Protein
H00002840-G01
Species: Hu
RNAi
GPR17 RNAi
GPR17 RNAi
H00002840-R02
Species: Hu

Description

GPR17, a former orphan G-coupled protein is specifically activated by P2Y and CysLT endogenous ligands, leading to both adenylyl cyclase inhibition and intracellular calcium increases. In both rats and humans GPR17 expressed in the organs which suffer ischemic damage, like the brain, heart and kidneys. Studies by Ciana, et. al. have shown that inhibition of GPR17 reduces ischemic damage in a rat focal ischemia model. These results suggest GPR17 is the common molecular target mediating brain damage by nucleotides and CysLTs.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 2840
Alternate Names
  • uracil nucleotide/cysteinyl leukotriene receptor
  • P2Y-like receptor
  • G-protein coupled receptor 17
  • DKFZp686M18273
  • R12
  • UDP/CysLT receptor
  • G protein-coupled receptor 17

Research Areas for GPR17

Find related products by research area and learn more about each of the different research areas below.

GPCR
Neuroscience

PTMs for GPR17

Learn more about PTMs related to GPR17.

Phosphorylation

Bioinformatics Tool for GPR17

Discover related pathways, diseases and genes to GPR17. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.