GIT1 Products

Description

G-protein-coupled receptor kinase interactor 1 (GIT1) and G-protein-coupled receptor kinase interactor 2 (GIT2) are GTPase-activating proteins for ADP-ribosylation (Arf) GTPases. GIT1 and GIT2 regulate Arf activity and the sequestration of activated G protein-coupled receptors from the surface of the cell. These activities have effects on multiple cellular processes such as cell migration, T-cell activation, and centrosome dynamics. Both GIT proteins also serve as scaffolds to link signaling molecules. Alternative names for GIT1 include GRK-interacting protein 1, cool-associated and tyrosine phosphorylated protein 1, and Cat-1.

Bioinformatics

Entrez	28964 Human
Uniprot	NP_054749 Human NP_054749.2 Human Q9Y2X7 Human
Product By Gene ID	28964
Alternate Names	ARF GAP GIT1 ARF GTPase-activating protein GIT1 CAT1 CAT-1 Cool-associated and tyrosine-phosphorylated protein 1 G protein-coupled receptor kinase interacting ArfGAP 1 G protein-coupled receptor kinase interactor 1 G protein-coupled receptor kinase-interactor 1 GRK-interacting protein 1

Research Areas for GIT1

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Phospho-Specific