GAT3 Products

Description

A prerequisite for fast synaptic transmission is a mechanism for rapid removal of transmitter molecules from the synaptic cleft, a task most often accomplished by transmitter clearance or degradation. High affinity transport proteins fulfill this role for a variety of neurotransmitters as is the case for GABA, the major inhibitory neurotransmitter in the CNS.Four transporters have been identified, referred to as GAT-1, GAT-2, GAT-3 (or GAT-B) and BGT-1, which transport GABA with varying affinities. GAT-3, identified in both neuronal and glial cells, transports both GABA and beta-alanine with relatively high affinity.

Bioinformatics

Entrez	79213 Rat
Product By Gene ID	6538
Alternate Names	GABA Transporter 3 GABT3 GAT-3 GAT3sodium- and chloride-dependent GABA transporter 3 GAT4 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 Solute carrier family 6 member 11

Research Areas for GAT3

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Neuroscience