GAB2 Products

Antibodies
GAB2 Antibody
GAB2 Antibody
AF4877
Species: Hu
Applications: WB
Host: Sheep Polyclonal
GAB2 Antibody
GAB2 Antibody
NBP1-81500
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
GAB2 Antibody
GAB2 Antibody
NB100-61653
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
GAB2 Overexpression Lysate (D ...
GAB2 Overexpression Lysate (Denatu...
H00009846-T01
Species: Hu
Applications: WB
GAB2 Overexpression Lysate (N ...
GAB2 Overexpression Lysate (Native)
NBP2-04413
Applications: WB
GAB2 Overexpression Lysate (N ...
GAB2 Overexpression Lysate (Native)
NBP2-07465
Applications: WB
Proteins
Recombinant Human GAB2 Protei ...
Recombinant Human GAB2 Protein
H00009846-P01
Species: Hu
Applications: WB, ELISA, PA
GAB2 Recombinant Protein Anti ...
GAB2 Recombinant Protein Antigen
NBP1-81500PEP
Species: Hu
Applications: AC

Description

Gab2 (Grb2-associated binder-2) is an adaptor protein involved in numerous intracellular signaling pathways via its interaction with receptor tyrosine kinases (RTKs), growth factors and cytokines. Gab2 is a substrate of various RTKs, including EGFR, insulin receptor, cytokine receptors as well as B and T cell antigen receptors; Gab2 acts as a docking protein for several SH2-containing proteins (1-3). Upon tyrosine phosphorylation, Gab2 interacts with SHP2 tyrosine phosphatase and GRB2 adaptor protein PI3-kinase, CrkL and SHC (4-5).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 9846
Alternate Names
  • GRB2-associated-binding protein 2
  • pp100
  • Growth factor receptor bound protein 2-associated protein 2
  • KIAA0571GRB2-associated binder 2
  • GRB2-associated binding protein 2

Research Areas for GAB2

Find related products by research area and learn more about each of the different research areas below.

Cancer

PTMs for GAB2

Learn more about PTMs related to GAB2.

Phosphorylation
Dephosphorylation
Cleavage
Methylation
Ribosylation
Myristoylation

Bioinformatics Tool for GAB2

Discover related pathways, diseases and genes to GAB2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related GAB2 Blog Posts

Check out the latest blog posts on GAB2.
CD19: An Undoubted Biomarker for B Cells
CD19 is a cell surface protein member of the large immunoglobulin superfamily that complexes with CD21, CD81, and CD225 in the membrane of mature B-cells. A major function of CD19 is to assemble with the antigen receptor of B-lymphocytes to decrease t...    Read more.
Read more GAB2 related blogs.