GAB2 Products

Antibodies
GAB2 Antibody
GAB2 Antibody
NBP1-81500
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
GAB2 Antibody
GAB2 Antibody
AF4877
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Formulation Catalog # Availability Price  
GAB2 Antibody
GAB2 Antibody
NB100-61653
Species: Hu, Mu, Rt, Ca
Applications: WB, ELISA
Host: Goat Polyclonal
Lysates
GAB2 Overexpression Lysate
GAB2 Overexpression Lysate
NBP2-04413
Species: Hu
Applications: WB
GAB2 Overexpression Lysate
GAB2 Overexpression Lysate
NBP2-07465
Species: Hu
Applications: WB
Proteins
Recombinant Human GAB2 GST (N ...
Recombinant Human GAB2 GST (N-Term...
H00009846-P01
Species: Hu
Applications: WB, ELISA, MA, AP
GAB2 Recombinant Protein Anti ...
GAB2 Recombinant Protein Antigen
NBP1-81500PEP
Species: Hu
Applications: AC

Description

Gab2 (Grb2-associated binder-2) is an adaptor protein involved in numerous intracellular signaling pathways via its interaction with receptor tyrosine kinases (RTKs), growth factors and cytokines. Gab2 is a substrate of various RTKs, including EGFR, insulin receptor, cytokine receptors as well as B and T cell antigen receptors; Gab2 acts as a docking protein for several SH2-containing proteins (1-3). Upon tyrosine phosphorylation, Gab2 interacts with SHP2 tyrosine phosphatase and GRB2 adaptor protein PI3-kinase, CrkL and SHC (4-5).

Bioinformatics

Entrez Mouse
Rat
Human
Uniprot Human
Human
Human
Human
Alternate Names
  • GRB2-associated binding protein 2
  • GRB2-associated-binding protein 2
  • Growth factor receptor bound protein 2-associated protein 2
  • KIAA0571GRB2-associated binder 2
  • pp100

Research Areas for GAB2

Find related products by research area and learn more about each of the different research areas below.

Cancer