Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE, Enzyme Activity
Description
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same isoform.
Bioinformatics
| Product By Gene ID |
2286 |
| Alternate Names |
- EC 5.2.1.8,13 kDa FK506-binding protein
- FK506 binding protein 2, 13kDa
- FK506-binding protein 2 (13kD)
- FK506-binding protein 2
- FKBP13
- FKBP13,13 kDa FKBP
- FKBP-13proline isomerase
- FKBP2
- FKBP-2
- Immunophilin FKBP13
- peptidyl-prolyl cis-trans isomerase FKBP2
- PPIase FKBP2
- PPIase
- rapamycin-binding protein
- rotamase
|
Research Areas for FKBP13/FKBP2
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction
