Species: Hu
Applications: Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: Flow, CyTOF-ready
Host: Goat Polyclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Applications: Bioactivity
Species: Hu
Applications: AC
Description
The FCRL3 gene codes for a member of the immunoglobulin receptor superfamily, a Fc receptor-like protein 3 that has seven isoforms: isoform 1: 734 amino acids long, 80 kDA; isoform 2: 639 amino acids long, nearly 70 kDA; isoform 3: 740 amino acids long, 81 kDA; isoform 4: 189 amino acids long, 21 kDA; isoform 5: 199 amino acids long, 22 kDA; isoform 6: 742 amino acid long, 81 kDA; and isoform 7: 707 amino acids long, 77 kDA. This protein functions in the moderation of the immune system as it obtains immunoreceptor-tyrosine activation motifs as well as immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain. It is known to interact with genes SYK, PTPN6, ZAP70, and PTPN11. FCRL3 is linked to multiple sclerosis, graves' disease, arthritis, lupus, rheumatoid arthritis, alopecia areata, behcet's disease, and primary biliary cirrhosis.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
115352 |
| Alternate Names |
- CD307c
- Fc receptor homolog 3
- Fc receptor-like 3
- Fc receptor-like protein 3
- FCRH3
- fcR-like protein 3
- hIFGP3
- IFGP3
- immunoglobulin superfamily receptor translocation associated protein 3
- IRTA3
- SPAP2
|
![Flow Cytometry FCRL3/FcRH3 Antibody (546828) [Unconjugated]](http://images.novusbio.com/fullsize2/FCRL3_MAB3126_Flow_Cytometry_12516.jpg)
![Binding Activity FCRL3/FcRH3 [Unconjugated]](http://images.novusbio.com/fullsize2/3126-fcb_recombinant-human-fcrl3-fcrh3-his-tag-protein-cf-binding-activity-4102022131939.jpg)
![SDS-PAGE FCRL3/FcRH3 [Unconjugated]](http://images.novusbio.com/fullsize2/3126-fcb_recombinant-human-fcrl3-fcrh3-his-tag-protein-cf-sds-page-219202214471.jpg)