FBXO31 Products

Antibodies
FBXO31 Antibody
FBXO31 Antibody
NBP1-19088
Species: Hu, Mu, Primate
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
FBXO31 Antibody
FBXO31 Antibody
NBP1-83916
Species: Hu, Mouse
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
FBXO31 Antibody (1H1)
FBXO31 Antibody (1H1)
NBP2-01508
Species: Hu
Applications: WB, Flow, ICC/IF
Host: Mouse Monoclonal
Lysates
FBXO31 Overexpression Lysate ...
FBXO31 Overexpression Lysate (Native)
NBL1-10631
Applications: WB
FBXO31 Overexpression Lysate ...
FBXO31 Overexpression Lysate (Dena...
H00079791-T01
Species: Hu
Applications: WB
Proteins
FBXO31 Recombinant Protein
FBXO31 Recombinant Protein
H00079791-P01
Species: Hu
Applications: WB, ELISA, PA
FBXO31 Partial Recombinant Pr ...
FBXO31 Partial Recombinant Protein
H00079791-Q01
Species: Hu
Applications: WB, ELISA, PA
FBXO31 Recombinant Protein An ...
FBXO31 Recombinant Protein Antigen
NBP1-83916PEP
Species: Hu
Applications: AC

Description

Belonging to the FBXO31 family, F-box only protein 31 (FBXO31) is a component of the SCF (SKP1-cullin-F-box) ubiquitin ligase complex and is involved in cyclin binding. At the protein level, FBXO31 plays a central role in G1 arrest following DNA damage. More specifically, these F-box proteins interact with SKP1 and recognize phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, thus resulting in G1 arrest. Diseases associated with FBXO31 include breast cancer, mast cell neoplasm, esophagitis and carcinoma.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 79791
Alternate Names
  • SCF ubiquitin ligase specificity factor
  • FBX31
  • putative breast cancer tumor-suppressor
  • F-box only protein 31
  • pp2386
  • MGC15419
  • MGC9527
  • Fbx31
  • FBXO14FLJ22477
  • FBX14DKFZp434J1815
  • DKFZp434B027
  • F-box protein 31

PTMs for FBXO31

Learn more about PTMs related to FBXO31.

Ubiquitination
Phosphorylation

Bioinformatics Tool for FBXO31

Discover related pathways, diseases and genes to FBXO31. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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