Factor XII heavy chain Products

Antibodies
Factor XII heavy chain Antibo ...
Factor XII heavy chain Antibody (3A3)
H00002161-M01
Species: Hu
Applications: WB, ELISA, PLA
Host: Mouse Monoclonal
Factor XII heavy chain Antibo ...
Factor XII heavy chain Antibody (1...
NBP2-41375
Species: Hu
Applications: WB, S-ELISA
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Factor XII heavy chain Antibo ...
Factor XII heavy chain Antibody (1...
NBP2-41377
Species: Hu
Applications: WB, ELISA(Cap)
Host: Mouse Monoclonal
Proteins
Factor XII heavy chain Recomb ...
Factor XII heavy chain Recombinant...
H00002161-P01
Species: Hu
Applications: WB, ELISA, PA
Factor XII heavy chain Recomb ...
Factor XII heavy chain Recombinant...
H00002161-P02
Species: Hu
Applications: WB, ELISA, PA
Factor XII heavy chain Partia ...
Factor XII heavy chain Partial Rec...
H00002161-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Factor XII heavy chain RNAi
Factor XII heavy chain RNAi
H00002161-R01
Species: Hu

Description

The F12 gene encodes a 615 amino acid long, 67 kDA serum glycoprotein coagulation factor XII that is eventually cleaved into four chains. Factor XII functions in the initiation of blood coagulation, fibrinolysis, as well as in the creation of bradykinin and angiotension. F12 participates in cell adhesion plasmin signaling, blood coagulation signaling pathways, MSP-RON signaling, intrinsic prothrombin activation pathways, and blood clotting cascades. It interacts with Genes CD93, MMP13, EPAS1, APP, and KLKB1. Defects in F12 lead to factor Xii deficiency (Hageman factor deficiency) as well as hereditary angioedema type 3 (estrogen-related HAE). F12 is also associated with blood clots, acute myocardial infarction, thrombosis, spastic paraplegia, angiodema, retinal vein occlusion, arterial calcification, heart disease, C1 inhibitor deficiency, hemorrhagic disease, and acalculous cholecystitis.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 2161
Alternate Names
  • EC 3.4.21
  • HAEX
  • coagulation factor XIIa light chain
  • HAE3
  • coagulation factor XIIa heavy chain
  • EC 3.4.21.38
  • coagulation factor XII
  • Hageman factor
  • HAFbeta-factor XIIa part 2
  • beta-factor XIIa part 1
  • coagulation factor XII (Hageman factor)

Bioinformatics Tool for Factor XII heavy chain

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