FACL4 Products

Description

The protein encoded by the FACL4 gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Althoughdiffering in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this familyconvert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis andfatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme maycontribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcriptvariants. (provided by RefSeq)

Bioinformatics

Entrez	113976 Rat 2182 Human 50790 Mouse
Uniprot	ACSL4_HUMAN Human NM_004458 Human NP_004449 Human NP_004449.1 Human NP_075266 Human O60488 Human
Product By Gene ID	2182
Alternate Names	ACS4mental retardation, X-linked 68 acyl-CoA synthetase 4 acyl-CoA synthetase long-chain family member 4 EC 6.2.1.3 FACL4long-chain 4 LACS 4 LACS4MRX68 lignoceroyl-CoA synthase Long-chain acyl-CoA synthetase 4 long-chain fatty-acid-Coenzyme A ligase 4 long-chain-fatty-acid--CoA ligase 4 mental retardation, X-linked 63 MRX63

Research Areas for FACL4

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism