F-Spondin/SPON1 Products

Antibodies
F-Spondin/SPON1 Antibody
F-Spondin/SPON1 Antibody
AF3135
Species: Hu
Applications: WB, Neut
Host: Goat Polyclonal
F-Spondin/SPON1 Antibody
F-Spondin/SPON1 Antibody
NB300-339
Species: Hu, Mu, Rt
Applications: WB, ICC/IF (-)
Host: Chicken Polyclonal
F-Spondin/SPON1 Antibody (3F4 ...
F-Spondin/SPON1 Antibody (3F4)
H00010418-M01
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Lysates
F-Spondin/SPON1 Overexpressio ...
F-Spondin/SPON1 Overexpression Lys...
NBL1-16417
Applications: WB
Proteins
F-Spondin/SPON1 Partial Recom ...
F-Spondin/SPON1 Partial Recombinan...
H00010418-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
F-Spondin/SPON1 RNAi
F-Spondin/SPON1 RNAi
H00010418-R01
Species: Hu

Description

SPON1 is a member of a subgroup of the thrombospondin type 1 (TSR) class molecules, defined by two domains of homology, the FS1/FS2 and TSR domains. The TSRs of SPON1 proteins are typical of class 2 TSRs. SPON1, which is similar to thrombospondin, is a extracellular matrix attached molecule that promotes neurite outgrowth and inhibits angiogenesis. Analysis of gain and loss of function experiments reveal that SPON1 is required for accurate pathfinding of embryonic axons, and plays a dual role in patterning axonal trajectories. It promotes the outgrowth of commissural and inhibits the outgrowth of motor axons, and has also been implicated in inflammatory processes in the nervous system.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 10418
Alternate Names
  • VSGP
  • Vascular smooth muscle cell growth-promoting factor
  • F-spondin
  • spondin 1, (f-spondin) extracellular matrix protein
  • spondin-1
  • f-spondin
  • KIAA0762VSGP/F-spondin
  • MGC10724
  • spondin 1, extracellular matrix protein

Research Areas for F-Spondin/SPON1

Find related products by research area and learn more about each of the different research areas below.

Neuroscience

PTMs for F-Spondin/SPON1

Learn more about PTMs related to F-Spondin/SPON1.

Cleavage
Phosphorylation
Glycosylation
C-mannosylation

Bioinformatics Tool for F-Spondin/SPON1

Discover related pathways, diseases and genes to F-Spondin/SPON1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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