ESAM Products

Description

ESAM is a tight junction regulatory protein involved in cell adhesion and is expressed only on endothelial cells and activated platelets. It may mediate aggregation through a homophilic molecular interaction (By similarity). ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel walls and it may have a role in signaling mechanisms that trigger the opening of endothelial cell contacts. A correlation has been found between ESAM expression and lymph node metastasis.

Bioinformatics

Entrez	90952 Human
Uniprot	AAH16868 Human AAH16868.1 Human NP_620411 Human
Product By Gene ID	90952
Alternate Names	2310008D05Rik endothelial cell adhesion molecule endothelial cell-selective adhesion molecule HUEL (C4orf1)-interacting protein LP4791 protein W117m