epithelial Sodium Channel beta Products

Antibodies
epithelial Sodium Channel bet ...
epithelial Sodium Channel beta Ant...
NBP1-84844
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
epithelial Sodium Channel bet ...
epithelial Sodium Channel beta Ant...
NBP2-59383
Species: Mu, Rt
Applications: WB, ICC/IF
Host: Mouse Monoclonal
epithelial Sodium Channel bet ...
epithelial Sodium Channel beta Ant...
NBP2-59382
Species: Mu, Rt
Applications: WB, IHC, IF
Host: Mouse Monoclonal
Lysates
epithelial Sodium Channel bet ...
epithelial Sodium Channel beta Ove...
NBL1-15746
Applications: WB
epithelial Sodium Channel bet ...
epithelial Sodium Channel beta Ove...
H00006338-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human epithelial ...
Recombinant Human epithelial Sodiu...
H00006338-P01
Species: Hu
Applications: WB, ELISA, PA
epithelial Sodium Channel bet ...
epithelial Sodium Channel beta Rec...
NBP1-84844PEP
Species: Hu
Applications: AC
RNAi
epithelial Sodium Channel bet ...
epithelial Sodium Channel beta RNAi
H00006338-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

SCNN1B is a subunit of the epithelial sodium channel, ENaC. ENac has high sodium selectivity, low conductance, and amiloride sensitivity. The functional channel of ENaC is composed of at least 3 subunits, alpha (SCNN1A), beta (SCNN1B), and gamma (SCNN1G). The 3 subunits show sequence similarities to one another, indicating descent from a common ancestral gene. Each encodes a protein containing 2 transmembrane domains, with intracellular amino and carboxyl termini. ENaC in the kidney, lung and colon plays an essential role in trans- epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium re-uptake in the distal nephron of the kidney, thus regulating blood pressure. Mutations in beta or gamma subunit of the epithelial sodium channel (ENaC) have been found to cause a hereditary form of human hypertension, Liddle syndrome.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Rat
Product By Gene ID 6338
Alternate Names
  • amiloride-sensitive sodium channel subunit beta 1
  • ENaCB
  • amiloride-sensitive sodium channel subunit beta
  • Beta-NaCH
  • ENaCb
  • Beta-ENaC
  • BESC1
  • nasal epithelial sodium channel beta subunit
  • SCNEB
  • epithelial sodium channel beta-3 subunit
  • Nonvoltage-gated sodium channel 1 subunit beta
  • epithelial sodium channel beta-2 subunit
  • Epithelial Na(+) channel subunit beta
  • beta-NaCH
  • ENaCbeta
  • beta-ENaC
  • sodium channel, nonvoltage-gated 1, beta

Research Areas for epithelial Sodium Channel beta

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Phospho-Specific

PTMs for epithelial Sodium Channel beta

Learn more about PTMs related to epithelial Sodium Channel beta.

Phosphorylation
Ubiquitination
Cleavage
Methylation

Bioinformatics Tool for epithelial Sodium Channel beta

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