eIF2A Products

Antibodies
eIF2A [p Ser51] Antibody
eIF2A [p Ser51] Antibody
NB100-81896
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
eIF2A Antibody (3A7B11)
eIF2A Antibody (3A7B11)
NBP2-26296
Species: Hu
Applications: WB, Flow, IHC
Host: Mouse Monoclonal
eIF2A Antibody (3A7A8)
eIF2A Antibody (3A7A8)
NBP2-37279
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Lysates
eIF2A Overexpression Lysate ( ...
eIF2A Overexpression Lysate (Native)
NBL1-10174
Applications: WB
eIF2A Overexpression Lysate ( ...
eIF2A Overexpression Lysate (Native)
NBP2-04263
Applications: WB
Proteins
eIF2A Recombinant Protein Ant ...
eIF2A Recombinant Protein Antigen
NBP1-84879PEP
Species: Hu
Applications: AC
Recombinant Human eIF2A Prote ...
Recombinant Human eIF2A Protein
H00083939-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
eIF2A RNAi
eIF2A RNAi
H00083939-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 83939
Alternate Names
  • EIF-2
  • eIF-2alpha
  • subunit 1 (alpha, 35kD )
  • EIF-2alpha
  • EIF2AEIF2
  • EIF-2A
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

Research Areas for eIF2A

Find related products by research area and learn more about each of the different research areas below.

Chromatin Research
DNA Repair
Lipid and Metabolism
Phospho-Specific
Translation Control
Unfolded Protein Response

PTMs for eIF2A

Learn more about PTMs related to eIF2A.

Phosphorylation
Cleavage
Dephosphorylation

Bioinformatics Tool for eIF2A

Discover related pathways, diseases and genes to eIF2A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related eIF2A Blog Posts

Check out the latest blog posts on eIF2A.
eIF2alpha - a regulator of global translation in response to cellular stress
Eukaryotic initiation factor 2 (eIF2) regulates global protein translation by binding to Met-tRNA and the 40S ribosome to form the pre-initiation complex. eIF2 is a heterotrimer consisting of alpha, beta, and gamma subunits. The 36kDA eIF2a subuni...    Read more.
PKR - Mediating cellular stress responses through multiple signaling pathways
Protein kinase R (PKR) is an intracellular stress-sensing protein that is able to detect and respond to viral infections. While PKR is able to sense and respond to a variety of signals, dsRNA is a well-characterized ligand. dsRNA produced during v...    Read more.
Read more eIF2A related blogs.