EBI3 Products

Description

EBI3 gene encodes a 229 amino acid long, 25 kDA interleukin-27 subunit beta protein that is member to the hematopoitetin receptor family. These proteins obtain pro as well as anti-inflammatory properties and have roles in T-helper cell development, suppressing cell proliferation, encouraging cytotoxic T-cell activity, and can induce isotope switching in B cells. EBI3 participates in Th1 differentiation, IL-2 signaling (and its primary biological effects in various immune cells), as well as IL27-mediated signaling events. EBI3 interacts with genes IL27, IL12A, CANX, MDF1, and SMAD3. It has been associated and researched in sepsis, asthma, carcinoma, Chron's disease, b-cell lymphomas, ulcerative colitis, Hodgkin disease, lymphoma, ebv infections, and glomerulonephritis.

Bioinformatics

Entrez	10148 Human 50498 Mouse
Uniprot	AAH15364 Human AAH15364.1 Human NP_005746 Human NP_005746.2 Human O35228 Mouse Q14213 Human
Product By Gene ID	10148
Alternate Names	cytokine receptor EBV-induced gene 3 protein Epstein-Barr virus induced 3 Epstein-Barr virus induced gene 3 Epstein-Barr virus-induced gene 3 protein IL-27 subunit beta IL27B IL-27B interleukin-27 subunit beta

Research Areas for EBI3

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Chemokine Research
Cytokine Research
Hypoxia
Immunology
Innate Immunity
Signal Transduction