Dynactin Subunit 1/DCTN1 Products

Antibodies
Dynactin Subunit 1/DCTN1 Anti ...
Dynactin Subunit 1/DCTN1 Antibody
NB100-1110
Species: Hu, Mu, Rb
Applications: WB, ELISA, Flow, Func, ICC/IF, IHC
Host: Goat Polyclonal
Dynactin Subunit 1/DCTN1 Anti ...
Dynactin Subunit 1/DCTN1 Antibody
NBP1-30880
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Dynactin Subunit 1/DCTN1 Anti ...
Dynactin Subunit 1/DCTN1 Antibody
NBP2-33976
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Lysates
Dynactin Subunit 1/DCTN1 Over ...
Dynactin Subunit 1/DCTN1 Overexpre...
NBL1-09749
Species: Hu
Applications: WB
Proteins
Recombinant Human Dynactin Su ...
Recombinant Human Dynactin Subunit...
H00001639-P01
Species: Hu
Applications: WB, ELISA, MA, AP
Dynactin Subunit 1/DCTN1 Reco ...
Dynactin Subunit 1/DCTN1 Recombina...
NBP3-21351PEP
Species: Hu
Applications: AC
Dynactin Subunit 1/DCTN1 Reco ...
Dynactin Subunit 1/DCTN1 Recombina...
NBP2-33976PEP
Species: Hu
Applications: AC

Description

The DCTN1 gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein. Alternative splicing of this gene results in at least 2 functionally distinct isoforms: a ubiquitously expressed one and a brain-specific one. Based on its cytogenetic location, this gene is considered as a candidate gene for limb-girdle muscular dystrophy.

Bioinformatics

Entrez Mouse
Human
Rat
Uniprot Human
Human
Human
Human
Alternate Names
  • dynactin 1 (p150, Glued (Drosophila) homolog)
  • dynactin 1
  • dynactin subunit 1
  • glued homolog, Drosophila)
  • p135
  • p150 Glued (Drosophila) homolog
  • p150-glued

Research Areas for Dynactin Subunit 1/DCTN1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication