Dynactin Subunit 1/DCTN1 Products

Antibodies
Dynactin Subunit 1/DCTN1 Anti ...
Dynactin Subunit 1/DCTN1 Antibody
AF6657
Species: Hu
Applications: WB, IHC
Host: Sheep Polyclonal
Dynactin Subunit 1/DCTN1 Anti ...
Dynactin Subunit 1/DCTN1 Antibody
NBP1-30880
Species: Hu, Rt, Mouse
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Dynactin Subunit 1/DCTN1 Anti ...
Dynactin Subunit 1/DCTN1 Antibody
NB100-1110
Species: Hu, Mu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
Lysates
Dynactin Subunit 1/DCTN1 Over ...
Dynactin Subunit 1/DCTN1 Overexpre...
NBL1-09749
Applications: WB
Proteins
Dynactin Subunit 1/DCTN1 Reco ...
Dynactin Subunit 1/DCTN1 Recombina...
H00001639-P01
Species: Hu
Applications: WB, ELISA, PA
Dynactin Subunit 1/DCTN1 Reco ...
Dynactin Subunit 1/DCTN1 Recombina...
NBP2-33976PEP
Species: Hu
Applications: AC
RNAi
Dynactin Subunit 1/DCTN1 RNAi ...
Dynactin Subunit 1/DCTN1 RNAi
H00001639-R02
Species: Hu
Dynactin Subunit 1/DCTN1 RNAi ...
Dynactin Subunit 1/DCTN1 RNAi
H00001639-R01
Species: Hu

Description

The DCTN1 gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein. Alternative splicing of this gene results in at least 2 functionally distinct isoforms: a ubiquitously expressed one and a brain-specific one. Based on its cytogenetic location, this gene is considered as a candidate gene for limb-girdle muscular dystrophy.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 1639
Alternate Names
  • p150 Glued (Drosophila) homolog
  • p150-glued
  • p135
  • dynactin subunit 1
  • dynactin 1 (p150, Glued (Drosophila) homolog)
  • glued homolog, Drosophila)
  • dynactin 1

Research Areas for Dynactin Subunit 1/DCTN1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for Dynactin Subunit 1/DCTN1

Learn more about PTMs related to Dynactin Subunit 1/DCTN1.

Phosphorylation
Cleavage

Bioinformatics Tool for Dynactin Subunit 1/DCTN1

Discover related pathways, diseases and genes to Dynactin Subunit 1/DCTN1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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