Species: Hu, Mu, Ze
Applications: WB, Flow
Host: Mouse Monoclonal
Species: Hu, Pm
Applications: WB, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Description
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
1787 |
| Alternate Names |
- DMNT2
- DNA (cytosine-5-)-methyltransferase 2
- DNA (cytosine-5)-methyltransferase-like protein 2
- DNA methyltransferase homolog HsaIIP
- DNA methyltransferase-2
- DNA MTase homolog HsaIIP
- DNMT2
- EC 2.1.1
- EC 2.1.1.29
- M.HsaIIP
- MHSAIIP
- PUMET
- RNMT1
- tRNA (cytosine-5-)-methyltransferase
- tRNA aspartic acid methyltransferase 1
|
Research Areas for Dnmt2
Find related products by research area and learn more about each of the different research areas below.
Chromatin ResearchEpigenetics
