DMPK Products

Antibodies
DMPK Antibody (713931)
DMPK Antibody (713931)
MAB6967
Species: Hu
Applications: WB
Host: Mouse Monoclonal
DMPK Antibody
DMPK Antibody
H00001760-D01P
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
DMPK Antibody (2F7)
DMPK Antibody (2F7)
H00001760-M01
Species: Hu
Applications: WB, ELISA, RNAi
Host: Mouse Monoclonal
Antibody Pairs
DMPK Antibody Pair
DMPK Antibody Pair
H00001760-PW1
Species: Hu
Applications: WB, IP
Lysates
DMPK Overexpression Lysate (N ...
DMPK Overexpression Lysate (Native)
NBP2-10661
Applications: WB
DMPK Overexpression Lysate (N ...
DMPK Overexpression Lysate (Native)
NBP2-10590
Applications: WB
DMPK Overexpression Lysate (D ...
DMPK Overexpression Lysate (Denatu...
H00001760-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human DMPK Protei ...
Recombinant Human DMPK Protein
H00001760-P01
Species: Hu
Applications: WB, ELISA, PA
DMPK Recombinant Protein Anti ...
DMPK Recombinant Protein Antigen
NBP1-85011PEP
Species: Hu
Applications: AC
DMPK Recombinant Protein Anti ...
DMPK Recombinant Protein Antigen
NBP1-85010PEP
Species: Hu
Applications: AC
RNAi
DMPK RNAi
DMPK RNAi
H00001760-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
DMPK RNAi
DMPK RNAi
H00001760-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Dystrophia myotonica protein kinase is encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 1760
Alternate Names
  • Myotonic dystrophy protein kinase
  • thymopoietin homolog
  • DM1PK
  • myotonin-protein kinase
  • DM1
  • DMmyotonin protein kinase A
  • MT-PKmyotonic dystrophy associated protein kinase
  • MDPKDM protein kinase
  • DMKEC 2.7.11.1
  • DM-kinase
  • dystrophia myotonica-protein kinase

Research Areas for DMPK

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

Bioinformatics Tool for DMPK

Discover related pathways, diseases and genes to DMPK. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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