DEC2/SHARP1 Products

Antibodies
DEC2/SHARP1 Antibody (5B1)
DEC2/SHARP1 Antibody (5B1)
NBP2-46574
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
DEC2/SHARP1 Antibody
DEC2/SHARP1 Antibody
AF5226
Species: Hu
Applications: WB
Host: Goat Polyclonal
Proteins
DEC2/SHARP1 Partial Recombina ...
DEC2/SHARP1 Partial Recombinant Pr...
H00079365-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
DEC2/SHARP1 RNAi
DEC2/SHARP1 RNAi
H00079365-R01
Species: Hu

Description

Human DEC1 is a 412 amino acid, basic helix-loop-helix (bHLH) containing protein that is involved in the control of proliferation and/or differentiation of several cell types including nerve cells, fibroblasts and chondrocytes. The bHLH region of DEC1 is structurally similar to the bHLH regions of the mammalian HES family, Drosophila hairy, and Enhancer of split m7. DEC1 is a novel direct target for cAMP in a wide range of cells, and is involved in the control of gene expression in cAMP-activated cells. DEC2, also known as SHARP1, is highly expressed in skeletal muscle and brain. The gene encoding human DEC2 maps to chromosome 12p11.23-p12.1. DEC1 and DEC2 play a role in regulating the mammalian molecular clock by suppressing the transcription of specific clock genes. Both DEC1 and DEC2 are detected in the suprachiasmimc nucleus in a circadian fashion. Brief light impulses induce the expression of DEC1 in a phase-dependent manner.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 79365
Alternate Names
  • bHLHe41
  • Class B basic helix-loop-helix protein 3
  • SHARP-1
  • bHLHb3
  • basic helix-loop-helix domain containing, class B, 3
  • BHLHB3class E basic helix-loop-helix protein 41
  • SHARP1hDEC2
  • DEC2Enhancer-of-split and hairy-related protein 1
  • Differentially expressed in chondrocytes protein 2
  • basic helix-loop-helix family, member e41

PTMs for DEC2/SHARP1

Learn more about PTMs related to DEC2/SHARP1.

Cleavage
Phosphorylation
Deacetylation
Ubiquitination

Bioinformatics Tool for DEC2/SHARP1

Discover related pathways, diseases and genes to DEC2/SHARP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related DEC2/SHARP1 Blog Posts

Check out the latest blog posts on DEC2/SHARP1.
SHARP1 - An enhancer-of-split- and hairy-related protein
SHARP1 encodes a transcription repressor factor that belongs to the Hairy/Enhancer of the Split subfamily of basic helix-loop-helix factors (bHLH). Sequence alignment shows that SHARP1 is only distantly related to these proteins with a 37-42% sequence...    Read more.
Read more DEC2/SHARP1 related blogs.