CXCL12/SDF-1 alpha Products

Description

For background information on chemokines, see CXCL11 (SCYB11; MIM 604852). Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF (see MIM 191160), or IL1 (see MIM 147760). The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.[supplied by OMIM]

Bioinformatics

Entrez	6387 Human
Uniprot	NP_001029058
Product By Gene ID	6387
Alternate Names	CXCL12 chemokine (C-X-C motif) ligand 12 CXCL12/SDF-1 alpha IRH PBSF SCYB12 SDF1 alpha SDF1 SDF1a SDF1B TLSF TPAR1

Research Areas for CXCL12/SDF-1 alpha

Find related products by research area and learn more about each of the different research areas below.

Biologically Active Proteins