CTDSPL Products

Description

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells

Bioinformatics

Entrez	10217 Human
Uniprot	NM_005808 Human NP_001008393 Human NP_001008393.1 Human NP_005799.2 Human O15194 Human Q3ZTU0 Human
Product By Gene ID	10217
Alternate Names	C3orf8 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase-like CTD small phosphatase-like protein CTDSP-like EC 3.1.3 hYA22 HYA22 NIF1 NIFL NIF-like protein NLI-interacting factor 1 Nuclear LIM interactor-interacting factor 1 Protein YA22 PSR1 RB protein serine phosphatase from chromosome 3 RBSP3EC 3.1.3.16 SCP3chromosome 3 open reading frame 8 Small CTD phosphatase 3 Small C-terminal domain phosphatase 3 YA22