Complement Factor B Products

Antibodies
Complement Factor B Antibody
Complement Factor B Antibody
NBP1-89985
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Complement Factor B Antibody
Complement Factor B Antibody
AF2739
Species: Hu
Applications: WB, IP
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Complement Factor B Antibody ...
Complement Factor B Antibody (313011)
MAB2739
Species: Hu
Applications: WB, IP
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human Complement Factor B ELI ...
Human Complement Factor B ELISA Ki...
NBP2-60564
Species: Hu
Applications: ELISA
Mouse Complement Factor B ELI ...
Mouse Complement Factor B ELISA Ki...
NBP2-75243
Species: Mu
Applications: ELISA
Rat Complement Factor B ELISA ...
Rat Complement Factor B ELISA Kit ...
NBP2-75244
Species: Rt
Applications: ELISA
Lysates
Complement Factor B Overexpre ...
Complement Factor B Overexpression...
NBL1-09119
Species: Hu
Applications: WB
Proteins
Complement Factor B Recombina ...
Complement Factor B Recombinant Pr...
NBP1-89985PEP
Species: Hu
Applications: AC
Complement Factor B Recombina ...
Complement Factor B Recombinant Pr...
NBP1-89986PEP
Species: Hu
Applications: AC
Recombinant Human Complement ...
Recombinant Human Complement Facto...
NBP2-22796
Species: Hu
Applications: PAGE

Description

Bomplement factor B is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 629
Alternate Names
  • C3/C5 convertase
  • EC 3.4.21
  • PBF2
  • glycine-rich beta-glycoprotein
  • BFD
  • C3 proactivator
  • Properdin factor B
  • C3 proaccelerator
  • Glycine-rich beta glycoprotein
  • FBI12
  • B-factor, properdin
  • FB
  • H2-Bf
  • GBGCFAB
  • BFAHUS4
  • EC 3.4.21.47
  • complement factor B

PTMs for Complement Factor B

Learn more about PTMs related to Complement Factor B.

Oxidation
Phosphorylation
Reduction
Nitration
Cleavage
Acetylation
Bromination

Bioinformatics Tool for Complement Factor B

Discover related pathways, diseases and genes to Complement Factor B. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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