COMP/Thrombospondin-5 Products

Description

COMP is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED)

Bioinformatics

Entrez	12845 Mouse 1311 Human 25304 Rat
Uniprot	ABM87644.1 Human NP_000086 Human P49747 Human
Product By Gene ID	1311
Alternate Names	cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia1, multiple) cartilage oligomeric matrix protein cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia1, multiple) EDM1 EPD1 MEDMGC131819 MGC149768 PSACH pseudoachondroplasia (epiphyseal dysplasia 1, multiple) THBS5 Thrombospondin-5 thrombospondin-5 TSP5