After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.
COMP is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED)
![Western Blot COMP/Thrombospondin-5 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/COMP_AF3134_Western_Blot_17834.jpg)
![Western Blot COMP/Thrombospondin-5 Antibody (360215) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/COMP_MAB3134_Western_Blot_17553.jpg)
![Sandwich ELISA COMP/Thrombospondin-5 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/COMP-Thrombospondin-5-Antibody-Pair-[Biotin]-Sandwich-ELISA-NBP2-79472-img0001.jpg)
![N/A COMP/Thrombospondin-5 [HRP]](http://images.novusbio.com/fullsize/elisa/DATA_COMP_DCMP0_ELISA_632.jpg)
![N/A COMP/Thrombospondin-5 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_COMP_DY3134_ELISA_1918.jpg)
![Binding Activity COMP/Thrombospondin-5 [Unconjugated]](http://images.novusbio.com/fullsize/protein/COMP_8958CP_1066.jpg)
![Neutralization COMP/Thrombospondin-5 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/COMP_AF3134_Block_Neutralize_8842.jpg)
![N/A COMP/Thrombospondin-5 [HRP]](http://images.novusbio.com/fullsize/elisa/COMP_DCMP0_ELISA_66.jpg)