Coagulation Factor III/Tissue Factor Products

Description

Tissue Factor encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [provided by RefSeq]

Bioinformatics

Entrez	2152 Human
Uniprot	AAH11029 Human AAH11029.1 Human NP_001984 Human NP_001984.1 Human P13726 Human
Product By Gene ID	2152
Alternate Names	CD142 antigen CD142 coagulation factor III (thromboplastin, tissue factor) Coagulation factor III FLJ17960 TF TFA Thromboplastin thromboplastin tissue factor

Research Areas for Coagulation Factor III/Tissue Factor

Find related products by research area and learn more about each of the different research areas below.

Cancer