Species: Hu
Applications: WB, Simple Western
Host: Goat Polyclonal
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Species: Hu, Mu, Rt, Ca
Applications: WB, ELISA
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Description
CILP, Cartilage Intermediate Layer Protein, is specifically expressed in the articular cartilage intermediate layer (it cannot be found in the superficial nor in the deepest layers) and is involved in scaffolding. Overexpression of this protein may lead to impairment of chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage. Antibodies against CILP are detected in patients with early-stage knee osteoarthritis and defects in this gene may be a cause of susceptibility to lumbar disk disease.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
8483 |
| Alternate Names |
- cartilage intermediate layer protein 1 C1
- cartilage intermediate layer protein 1 C2
- cartilage intermediate layer protein 1
- cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
- Cartilage intermediate-layer protein
- CILP-1
- HsT18872
|
Research Areas for CILP-1
Find related products by research area and learn more about each of the different research areas below.
Immune System DiseasesImmunology
![Western Blot CILP-1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/CILP-1_AF5504_Western_Blot_5738.jpg)
![Simple Western CILP-1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/CILP1_AF5504_Simple_Western_17022.jpg)
