CIB1 Products

Description

CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

Bioinformatics

Entrez	10519 Human
Uniprot	AAH00846 Human AAH00846.1 Human NM_006384 Human NP_006375 Human
Product By Gene ID	10519
Alternate Names	calcium and integrin binding 1 (calmyrin) Calcium- and integrin-binding protein CALMYRIN Calmyrin calmyrin CIBcalcium and integrin binding protein CIBP DNA-dependent protein kinase interacting protein DNA-PKcs-interacting protein Kinase-interacting protein KIP1 KIPcalcium and integrin binding, protein kinase interacting protein PRKDCIP SIP2-28calcium and integrin-binding protein 1 Snk interacting protein 2-28 SNK-interacting protein 2-28

Related CIB1 Blog Posts

Check out the latest blog posts on CIB1.

IRE1 alpha dependent apoptotic-signaling pathway Despite in depth characterization of the role of IRE1 alpha (inositol-requiring enzyme 1 alpha) in activating the unfolded protein response (UPR) in the ER - little is known about the molecular mechanisms by which this ER protein has shown to reg...    Read more.

Read more CIB1 related blogs.