CEACAM5/CD66e Products

Description

The CD66e (CEA; 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion. Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting.

Bioinformatics

Entrez	1048 Human 1084 Human
Uniprot	AAH34671 Human AAH34671.1 Human NP_001806 Human NP_004354 Human P06731 Human P40198 Human
Product By Gene ID	1048
Alternate Names	Carcinoembryonic antigen carcinoembryonic antigen-related cell adhesion molecule 5 CD66e antigen CEACD66e DKFZp781M2392 Meconium antigen 100

Research Areas for CEACAM5/CD66e

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
Immunology