CDK8 Products

Antibodies
CDK8 Antibody (5H4)
CDK8 Antibody (5H4)
H00001024-M03
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Mouse Monoclonal
CDK8 Antibody (6H5)
CDK8 Antibody (6H5)
H00001024-M01
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Mouse Monoclonal
CDK8 Antibody (6E5.)
CDK8 Antibody (6E5.)
H00001024-M02
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
CDK8 Overexpression Lysate (N ...
CDK8 Overexpression Lysate (Native)
NBL1-09046
Applications: WB
Proteins
Recombinant Human CDK8 Protei ...
Recombinant Human CDK8 Protein
H00001024-Q01
Species: Hu
Applications: WB, ELISA, PA
CDK8 Recombinant Protein Anti ...
CDK8 Recombinant Protein Antigen
NBP2-55134PEP
Species: Hu
Applications: AC
RNAi
CDK8 RNAi
CDK8 RNAi
H00001024-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Cdk8 is encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 1024
Alternate Names
  • EC 2.7.11
  • Protein kinase K35
  • EC 2.7.11.23
  • Mediator of RNA polymerase II transcription subunit CDK8
  • EC 2.7.11.22
  • Mediator complex subunit CDK8
  • CDK8 protein kinase
  • Cell division protein kinase 8
  • MGC126075
  • K35
  • MGC126074
  • cyclin-dependent kinase 8

Research Areas for CDK8

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for CDK8

Learn more about PTMs related to CDK8.

Phosphorylation
Acetylation
Cleavage
Ubiquitination
Dephosphorylation
Methylation

Bioinformatics Tool for CDK8

Discover related pathways, diseases and genes to CDK8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related CDK8 Blog Posts

Check out the latest blog posts on CDK8.
Notch1 - A multifunctional transmembrane receptor
Notch1 is a member of the Notch family of Type 1 single-pass transmembrane proteins that share an extracellular domain of multiple epidermal growth factor-like (EGF) repeats. Notch family members play key roles in a variety of developmental process...    Read more.
Read more CDK8 related blogs.