BNIP2 Products

Antibodies
BNIP2 Antibody
BNIP2 Antibody
NBP1-88559
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
BNIP2 Antibody
BNIP2 Antibody
NBP2-15602
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
BNIP2 Antibody
BNIP2 Antibody
NBP1-19759
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
BNIP2 Overexpression Lysate ( ...
BNIP2 Overexpression Lysate (Native)
NBL1-08013
Applications: WB
Proteins
BNIP2 Recombinant Protein
BNIP2 Recombinant Protein
H00000663-P01
Species: Hu
Applications: WB, ELISA, PA
BNIP2 Recombinant Protein Ant ...
BNIP2 Recombinant Protein Antigen
NBP1-88559PEP
Species: Hu
Applications: AC

Description

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 663
Alternate Names
  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
  • BCL2/adenovirus E1B 19kD-interacting protein 2
  • Nip2
  • NIP2
  • BNIP-2
  • BCL2/adenovirus E1B 19kDa interacting protein 2

Research Areas for BNIP2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

PTMs for BNIP2

Learn more about PTMs related to BNIP2.

Cleavage
Phosphorylation

Bioinformatics Tool for BNIP2

Discover related pathways, diseases and genes to BNIP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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