Bad Products

Antibodies
Bad Antibody
Bad Antibody
NB100-56080
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Bad Antibody [Unconjugated]
Bad Antibody [Unconjugated]
AF819
Species: Hu, Mu
Applications: WB, ICC
Host: Rabbit Polyclonal
Bad Antibody (612312) [Unconj ...
Bad Antibody (612312) [Unconjugated]
MAB6405
Species: Hu
Applications: WB, IHC, ICC
Host: Mouse Monoclonal
Lysates
Bad Overexpression Lysate (Na ...
Bad Overexpression Lysate (Native)
NBP2-07881
Applications: WB
Bad Overexpression Lysate (Na ...
Bad Overexpression Lysate (Native)
NBL1-07900
Applications: WB
Bad Overexpression Lysate (Na ...
Bad Overexpression Lysate (Native)
NBP2-09800
Applications: WB
Proteins
Bad Recombinant Protein
Bad Recombinant Protein
H00000572-P01
Species: Hu
Applications: WB, ELISA, PA
Bad Partial Recombinant Prote ...
Bad Partial Recombinant Protein
H00000572-Q01
Species: Hu
Applications: WB, ELISA, PA
Bad Recombinant Protein Antig ...
Bad Recombinant Protein Antigen
NBP2-38947PEP
Species: Hu
Applications: AC
RNAi
Bad RNAi
Bad RNAi
H00000572-R01
Species: Hu
Bad RNAi
Bad RNAi
H00000572-R02
Species: Hu

Description

Bad is a pro-apoptotic member of the Bcl-2 family. Bad will bind preferentially Bcl-xL over Bcl-2 through its partial (9-16 a.a) BH3 domain. Additionally, Bad can reverse the death repressor activity of Bcl-xL but not of Bcl-2. Upon dephosphorylation, activated Bad translocates to the mitochondria and displace Bcl-2 from tBid sequestration to initiate mitochondrial dysfunction. The switching on/off of its phosphorylation by growth/survival factors regulates Bad activity.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 572
Alternate Names
  • Bcl2-L-8
  • BCL-X/BCL-2 binding protein
  • BBC6
  • Bcl-XL/Bcl-2-associated death promoter
  • BCL2-binding protein
  • Bcl-2-like protein 8
  • BCL2-binding component 6
  • Bcl-2-binding component 6
  • BCL2-antagonist of cell death protein
  • BBC2
  • BCL2L8bcl2-L-8
  • bcl2 antagonist of cell death
  • BCL2-associated agonist of cell death

Research Areas for Bad

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Apoptosis
Cancer
GPCR
Neuroscience
Phospho-Specific
Tumor Suppressors

Bioinformatics Tool for Bad

Discover related pathways, diseases and genes to Bad. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

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AKT Antibody Assays: A Complex Area with an Easy Solution
We at Novus Biologicals place a lot of emphasis on the kinase signaling pathways. Kinases, or phosphotransferase enzymes play a key role in phosphorylation signaling. Over 500 human protein kinases have so far been discovered. They play essential role...    Read more.
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