B-Raf Products

Antibodies
B-Raf Antibody (5A9)
B-Raf Antibody (5A9)
Species: Hu, Mk
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
B-Raf Antibody
B-Raf Antibody
NBP1-89942
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
B-Raf Antibody [Unconjugated] ...
B-Raf Antibody [Unconjugated]
AF3424
Species: Hu
Applications: WB, Simple Western
Host: Goat Polyclonal
Lysates
B-Raf Overexpression Lysate ( ...
B-Raf Overexpression Lysate (Native)
NBL1-08021
Applications: WB
Proteins
B-Raf Recombinant Protein Ant ...
B-Raf Recombinant Protein Antigen
NBP1-89942PEP
Species: Hu
Applications: AC
B-Raf Recombinant Protein
B-Raf Recombinant Protein
NBP2-51931
Species: Hu
Applications: PAGE
B-Raf Peptide
B-Raf Peptide
NBP1-76269PEP
Species: Hu
Applications: AC
RNAi
B-Raf RNAi
B-Raf RNAi
H00000673-R03
Species: Hu

Description

B-Raf, also know as c-Rmil, is a Serine/Threonine protein kinase member of the Raf family which includes Raf-1 and A-Raf. B-Raf is involved in the transduction of mitogenic signals from the cell membrane to the nucleus (1). Composed of three conserved region (CR1, CR2, CR3) B-Raf is expressed primarily in the brain and in the nervous system (2). It has been observed that MAPK is activated by B-Raf in response to nerve growth factor (3). More than 60% of malignant melanomas were found to contain a specific mutation, B-Raf (V599E) the product of which possesses constitutive kinase activity (4). Mutations in B-Raf have also been identified in lung cancer and non-Hodgkin lymphoma.

Bioinformatics

Entrez Human
Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 673
Alternate Names
  • B-RAF1
  • EC 2.7.11.1
  • 94 kDa B-raf protein
  • serine/threonine-protein kinase B-raf
  • NS7
  • murine sarcoma viral (v-raf) oncogene homolog B1
  • p94
  • B-Raf proto-oncogene serine/threonine-protein kinase (p94)
  • RAFB1
  • MGC138284
  • Proto-oncogene B-Raf
  • BRAF1MGC126806
  • v-raf murine sarcoma viral oncogene homolog B1FLJ95109

Research Areas for B-Raf

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Phospho-Specific

Bioinformatics Tool for B-Raf

Discover related pathways, diseases and genes to B-Raf. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related B-Raf Blog Posts

Check out the latest blog posts on B-Raf.
MAPK3/ERK1 - A signal transduction pathway with roles in development and disease
Mitogen-activated protein kinases (MAPKs) are important signaling proteins needed to transmit and relay extracellular stimuli and to illicit intracellular responses (1). The MAPK family of proteins are serine/threonine kinases that are able to phos...    Read more.
You can't be without me - SNF5
The protein encoded by SNF5 is a component of the chromatin-remodeling protein complex responsible for relieving repressive chromatin structures by allowing the transcriptional machinery to access targets more effectively. SNF5 has been found to be a...    Read more.
Read more B-Raf related blogs.