Aurora C Products

Antibodies
Lysates
Aurora C Overexpression Lysat ...
Aurora C Overexpression Lysate
NBL1-07862
Species: Hu
Applications: WB
Proteins
Recombinant Human Aurora C Pr ...
Recombinant Human Aurora C Protein
H00006795-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human Aurora C Pr ...
Recombinant Human Aurora C Protein
H00006795-P01
Species: Hu
Applications: WB, ELISA, PA, AP
Aurora C Recombinant Protein ...
Aurora C Recombinant Protein Antigen
NBP1-90819PEP
Species: Hu
Applications: AC

Description

Aurora-C is a member of a novel family of serine/threonine kinases that have been identified as key regulators of the mitotic cell division process (1). Studies show that human Aurora-C is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere protein (INCENP), which are known passenger proteins. INCENP binds and activates Aurora-C in vivo and in vitro. Aurora-C co-expressed with INCENP elicits the phosphorylation of endogenous histone H3 in mammalian cells, even though this phosphorylation is not sufficient to establish chromosome condensation in interphase cells (2). Over-expression of an inactive mutant of Aurora C impaired the localization of Aurora C to the spindle midzone resulting in multinucleation which demonstrates that Aurora C is required for cytokinesis (3).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 6795
Alternate Names
  • EC 2.7.11
  • Aurora/IPL1-related kinase 3
  • serine/threonine-protein kinase 13
  • Aurora-related kinase 3
  • aurora-C
  • serine/threonine kinase 13 (aurora/IPL1-like)
  • EC 2.7.11.1
  • AurC
  • STK13ARK-3
  • AIE2AIK3
  • ARK3Serine/threonine-protein kinase aurora-C
  • aurora kinase CAurora/IPL1/Eg2 protein 2

Research Areas for Aurora C

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for Aurora C

Learn more about PTMs related to Aurora C.

Phosphorylation

Bioinformatics Tool for Aurora C

Discover related pathways, diseases and genes to Aurora C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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