Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Flow
Host: Mouse Monoclonal
Species: Hu, Rt, Bv, Ca
Applications: WB, ELISA
Host: Goat Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP, Enzyme Activity
Species: Hu
Applications: AC
Description
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human |
| Product By Gene ID |
1386 |
| Alternate Names |
- activating transcription factor 2formerly
- ATF2
- cAMP responsive element binding protein 2
- cAMP-responsive element-binding protein 2
- CREB2
- CREBP1
- CRE-BP1
- cyclic AMP-dependent transcription factor ATF-2
- HB16
- MGC111558
- mXBP
- TREB7
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