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ATF-2 (activating transcription factor-2, CRE-BP1) is a transcription factor that binds the cAMP response element (CRE) and AP-1 response element and is abundantly expressed in the brain. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines, and UV irradiation, stimulate the transcriptional activity of ATF-2 (2). SAPK and p38 MAPK can activate, in response to cellular stress, ATF-2 by phosphorylating this protein at Thr69 and Thr71. Mutations of these sites result in the loss of stress-induced transcription by ATF-2 (2-4).
![Western Blot ATF2 [p Thr69] Antibody - BSA Free](http://images.novusbio.com/fullsize/ATF2-[p-Thr69]-Antibody-Western-Blot-NB100-81798-img0004.jpg)
![Immunohistochemistry-Paraffin ATF2 [p Thr69] Antibody - BSA Free](http://images.novusbio.com/fullsize/nb100-81798_rabbit-polyclonal-atf2-p-thr69-antibody-10320252332104.jpg)
![Western Blot ATF2 [p Thr69] Antibody - BSA Free](http://images.novusbio.com/fullsize/nb100-81798_rabbit-polyclonal-atf2-p-thr69-antibody-10320252347260.jpg)
![Immunocytochemistry/ Immunofluorescence ATF2 [p Thr69] Antibody - BSA Free](http://images.novusbio.com/fullsize/nb100-81798_rabbit-polyclonal-atf2-p-thr69-antibody-1132025155590.jpg)
![Western Blot ATF2 [p Thr71] Antibody (103C411.2)](http://images.novusbio.com/fullsize/ATF2-p-Thr71-Antibody-103C411-2-Western-Blot-NB100-56594-img0003.jpg)
