Applications: WB, Flow
Host: Mouse Monoclonal
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
WB, ELISA, PA, AP
Applications: WB, ELISA, PA, PAGE, AP
Applications: WB, ELISA, PA, AP
ATF-2 (activating transcription factor-2, CRE-BP1) is a transcription factor that binds the cAMP response element (CRE) and AP-1 response element and is abundantly expressed in the brain. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines, and UV irradiation, stimulate the transcriptional activity of ATF-2 (2). SAPK and p38 MAPK can activate, in response to cellular stress, ATF-2 by phosphorylating this protein at Thr69 and Thr71. Mutations of these sites result in the loss of stress-induced transcription by ATF-2 (2-4).
Bioinformatics Tool for ATF2
Discover related pathways, diseases and genes to ATF2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.