ARNT/HIF-1 beta Products

Antibodies
ARNT/HIF-1 beta Antibody
ARNT/HIF-1 beta Antibody
NB100-110
Species: Hu, Mu, Rt, Bv, Ft, Sh
Applications: WB, Simple Western, ChIP, ICC/IF, IHC, IHC-P, IP, GS
Host: Rabbit Polyclonal
ARNT/HIF-1 beta Antibody (2B1 ...
ARNT/HIF-1 beta Antibody (2B10)
NB300-525
Species: Hu, Mu, Rt, Am, Pm, Ze
Applications: WB, GS, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
Antibody Packs
ARNT/HIF-1 beta Antibody Pack ...
ARNT/HIF-1 beta Antibody Pack
NB100-982
Species: Hu, Mu, Rt, Bv, Ft, Sh
Applications: WB, ChIP, IHC, IHC-P, IP
Host: Mouse
Lysates
ARNT/HIF-1 beta Overexpressio ...
ARNT/HIF-1 beta Overexpression Lys...
H00000405-T01
Species: Hu
Applications: WB
ARNT/HIF-1 beta Overexpressio ...
ARNT/HIF-1 beta Overexpression Lys...
NBL1-07720
Applications: WB
Proteins
ARNT/HIF-1 beta Recombinant P ...
ARNT/HIF-1 beta Recombinant Protein
H00000405-P01
Species: Hu
Applications: WB, ELISA, PA
ARNT/HIF-1 beta Partial Recom ...
ARNT/HIF-1 beta Partial Recombinan...
H00000405-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
ARNT/HIF-1 beta RNAi
ARNT/HIF-1 beta RNAi
H00000405-R01V
Species: Hu
Applications: WB, RNAi SP
ARNT/HIF-1 beta RNAi
ARNT/HIF-1 beta RNAi
H00000405-R01
Species: Hu
ARNT/HIF-1 beta RNAi
ARNT/HIF-1 beta RNAi
H00000405-R02
Species: Hu

Description

HIF-1 beta (ARNT) and HIF-1 alpha are subunits of HIF-1 which is a nuclear protein involved in mammalian oxygen homeostasis. Both subunits are constantly translated. However, under normoxic conditions, human HIF-1 alpha is hydroxylated at Pro402 or Pro564 by a set of HIF prolyl hydroxylases, is polyubiquinated, and eventually degraded in proteosomes. Under hypoxic conditions, the lack of hydroxylation prevents HIF degradation and increases transcriptional activity. Therefore, the concentration of HIF-1 alpha increases in the cell. In contrast, HIF-1 beta remains stable under either condition. HIF-1 beta is a series of aryl hydrocarbon receptor nuclear translocator (ARNT) gene products.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 405
Alternate Names
  • HIF-1 Beta
  • HIF1BETA
  • Hypoxia-inducible factor 1-beta
  • HIF1B
  • ARNT protein
  • HIF1-beta
  • BHLHE2
  • HIF-1-beta
  • hypoxia-inducible factor 1, beta subunit
  • nuclear translocator
  • aryl hydrocarbon receptor nuclear translocator

Research Areas for ARNT/HIF-1 beta

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Autophagy
Cancer
Cellular Markers
Chromatin Research
HIF Target Genes
Hypoxia
Transcription Factors and Regulators

Bioinformatics Tool for ARNT/HIF-1 beta

Discover related pathways, diseases and genes to ARNT/HIF-1 beta. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related ARNT/HIF-1 beta Blog Posts

Check out the latest blog posts on ARNT/HIF-1 beta.
HIF-2 alpha: HIF1A's Homologue with Similar and Divergent Functions
HIF-2 alpha is a member of the heterodimeric hypoxia-inducible factors/HIFs family (HIF-1, HIF-2, and HIF-3) which contains a common beta subunit but differ in their alpha subunits. Also called as EPAS1 or Mop2, HIF-2 alpha regulates cellular adapt...    Read more.
HIF-3 alpha: a versatile target with hypoxia dependent and independent functions
By: Subhash GangarHIF-3 alpha (hypoxia-inducible factor 3-alpha/ HIF3A) represents an isoform of HIF-alpha subunits which heterodimerize with stable beta subunit (HIF-beta) for the regulation of HIF target genes through binding to hypoxia respon...    Read more.
HIF-1 beta - activating gene transcription in response to hypoxia
Hypoxia-inducible factor 1 (HIF-1) is a heterodimeric transcription factor consisting of alpha and beta subunits. The levels of functional HIF-1 in the cell depends on the level of oxygen allowing cells to respond to hypoxic conditions. HIF-1a is a...    Read more.
Read more ARNT/HIF-1 beta related blogs.