ARMER Products

Antibodies
ARMER Antibody
ARMER Antibody
NBP1-77198
Species: Hu, Mu
Applications: WB, ELISA, IHC, IHC-P, IF
Host: Rabbit Polyclonal
ARMER Antibody
ARMER Antibody
NBP1-91681
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ARMER Antibody
ARMER Antibody
NBP1-02970
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ARMER Overexpression Lysate ( ...
ARMER Overexpression Lysate (Denat...
H00023204-T01
Species: Hu
Applications: WB
ARMER Overexpression Lysate ( ...
ARMER Overexpression Lysate (Native)
NBL1-07700
Applications: WB
Proteins
ARMER Recombinant Protein
ARMER Recombinant Protein
H00023204-P01
Species: Hu
Applications: WB, ELISA, PA
ARMER Recombinant Protein Ant ...
ARMER Recombinant Protein Antigen
NBP1-91681PEP
Species: Hu
Applications: AC
ARMER Peptide
ARMER Peptide
NBP1-77198PEP
Species: Hu
Applications: AC
RNAi
ARMER RNAi
ARMER RNAi
H00023204-R01
Species: Hu

Description

Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA. Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12, other caspases such as caspase-9 are also thought to be activated following ER stress. Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity (3), although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 23204
Alternate Names
  • ARL-6-interacting protein 1
  • Aip-1
  • ARMER
  • apoptotic regulator in the membrane of the endoplasmic reticulum
  • AIP1
  • ARL6IPaip-1
  • KIAA0069ADP-ribosylation factor-like protein 6-interacting protein 1
  • ADP-ribosylation factor-like 6 interacting protein
  • ADP-ribosylation factor-like 6 interacting protein 1

Research Areas for ARMER

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

PTMs for ARMER

Learn more about PTMs related to ARMER.

Ribosylation
Cleavage

Bioinformatics Tool for ARMER

Discover related pathways, diseases and genes to ARMER. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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