Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Species: Hu, Mu, Po, Bv
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
APPL is encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Bioinformatics
| Product By Gene ID |
26060 |
| Alternate Names |
- Adapter protein containing PH domain, PTB domain and leucine zipper motif 1
- adaptor protein containing pH domain, PTB domain and leucine zipper motif 1
- adaptor protein, phosphotyrosine interaction, PH domain and leucine zippercontaining 1
- AKT2 interactor
- APPL
- APPL1
- APPLdip13-alpha
- DCC-interacting protein 13-alpha
- DIP 13 alpha
- DIP13A
- DIP13alpha
- Dip13-alpha
- KIAA1428
- signaling adaptor protein DIP13alpha
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