APPL Products

Description

APPL is encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Bioinformatics

Entrez	26060 Human
Uniprot	NM_012096 Human NP_036228 Human NP_036228.1 Human Q9UKG1 Human
Product By Gene ID	26060
Alternate Names	Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 adaptor protein containing pH domain, PTB domain and leucine zipper motif 1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zippercontaining 1 AKT2 interactor APPLdip13-alpha DCC-interacting protein 13-alpha DIP 13 alpha DIP13A DIP13alpha Dip13-alpha KIAA1428 signaling adaptor protein DIP13alpha