APP Products

Antibodies
APP Antibody (7G9)
APP Antibody (7G9)
Species: Hu, Mk
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
APP Antibody
APP Antibody
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
APP Antibody - Pan Specific
APP Antibody - Pan Specific
AF1168
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
ELISA Kits
APP ELISA Kit [Biotin]
APP ELISA Kit [Biotin]
KA2105
Species: Hu
Lysates
APP Overexpression Lysate (Na ...
APP Overexpression Lysate (Native)
NBP2-04578
Applications: WB
APP Overexpression Lysate (Na ...
APP Overexpression Lysate (Native)
NBP2-09023
Applications: WB
APP Overexpression Lysate (Na ...
APP Overexpression Lysate (Native)
NBL1-07632
Applications: WB
Proteins
APP Recombinant Protein
APP Recombinant Protein
H00000351-P01
Species: Hu
Applications: WB, ELISA, PA
APP Recombinant Protein Antig ...
APP Recombinant Protein Antigen
NBP1-90246PEP
Species: Hu
Applications: AC
APP Recombinant Protein
APP Recombinant Protein
NBP1-99026
Species: Hu
Applications: PAGE
RNAi
APP RNAi
APP RNAi
H00000351-R01
Species: Hu
APP RNAi
APP RNAi
H00000351-R03
Species: Hu
APP RNAi
APP RNAi
H00000351-R02
Species: Hu

Description

Alzheimer's disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (A 4) protein has been found to be the principal constituent of senile plaques of AD's patients (1-2). The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4 kDa A 4 protein. Two variants of A 4 can be detected; A 1-40 "short-tailed" and A 1-42 "long-tailed" (3-4).

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Rat
Product By Gene ID 351
Alternate Names
  • Amyloid beta precursor protein
  • APP
  • amyloid beta A4 precursor protein-binding family B member 2
  • amyloid beta (A4) precursor protein-binding, family B, member 2

Research Areas for APP

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Apoptosis
Cell Cycle and Replication
Neurodegeneration
Neuronal Cell Markers
Neuroscience
Phospho-Specific

Bioinformatics Tool for APP

Discover related pathways, diseases and genes to APP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related APP Blog Posts

Check out the latest blog posts on APP.
Niemann Pick-C1 and cholesterol dynamics
Niemann-Pick type C1 (NPC1) mediates low-density cholesterol transport from late endosomes and lysosomes to other areas of the cell via receptor mediation endocytosis.  Although cholesterol moves freely inside the cell, it cannot independently expo...    Read more.
FANCD2 and DNA damage repair
Fanconi anemia (FA) is a genetically inherited disorder that yields cytogenetic instability, hypersensitivity to DNA crosslinking compounds and defective DNA repair. A variety of genes have been identified within the FA pathway that are referred t...    Read more.
Beta Amyloid Neurotoxicity and Alzheimer's Disease
A major histopathological hallmark of Alzheimer's disease (AD) is the presence of amyloid deposits in the parenchyma of the amygdala, hippocampus, and neocortex. The principal component of amyloid is beta amyloid (AB). The pathologic accumulation of A...    Read more.
ApoE: The Key to Preventing Alzheimer's Disease?
Apolipoprotein E also known as ApoE is a 36kDa protein that is expressed in all lipoprotein fractions in plasma. This protein is produced in high quantities in the liver, brain, spleen, lung and kidney. The function of APOE is to mediate the binding,...    Read more.
Amyloid beta and Methionine Sulfoxide Related to Abeta 42 Antibody and Abeta 40 Antibody
By Eric NeeleyAlzheimer's disease is a devastating neurodegenerative illness characterized by the formation of plaques, tangles, and eventually synaptic loss. Amyloid beta (A beta ) is the processed form of the Amyloid precursor protein (APP), and whose...    Read more.
Read more APP related blogs.