Alpha-mannosidase II Products

Description

Alpha-mannosidase II encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq]

Bioinformatics

Entrez	4124 Human
Uniprot	Q16706 Human NP_002363 Human NP_002363.2 Human NM_002372 Human
Product By Gene ID	4124
Alternate Names	EC 3.2.1 Golgi alpha-mannosidase II Mannosidase alpha class 2A member 1 AMan II mannosidase, alpha type II Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase golgi integral membrane protein 7 Man II alpha-mannosidase 2 GOLIM7 MANA2MANII EC 3.2.1.114 mannosidase, alpha, class 2A, member 1

Diseases related to Alpha-mannosidase II

Discover more about diseases related to Alpha-mannosidase II.

Cholangiocarcinoma
Autoimmunity
Anemia
Nerve Degeneration
Congenital Dyserythropoietic Anemia
Acute Lymphocytic Leukemia
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Leukemia
Lupus Erythematosus, Systemic
Inflammation
L1 Acute Lymphoblastic Leukemia
Alzheimer's Disease

Pathways for Alpha-mannosidase II

View related products by pathway and learn more about each of the pathways below.

Glycosylation
Localization
Flight

PTMs for Alpha-mannosidase II

Learn more about PTMs related to Alpha-mannosidase II.

Glycosylation

Bioinformatics Tool for Alpha-mannosidase II

Discover related pathways, diseases and genes to Alpha-mannosidase II. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.