alpha-Defensin 1 Products

Description

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 3 by only one amino acid. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	1667
Alternate Names	alpha 2 alphaDefensin 1 alpha-Defensin 1 DEF1 DEF1DEFA1B DEFA1 DEFA2 defensin, alpha 1, myeloid-related sequence defensin, alpha 1HP-1 HNP-1 HNP-1HP1 HP1 MRS MRSMGC138393 myeloid-related sequence neutrophil defensin 1

Research Areas for alpha-Defensin 1

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Cancer

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Toll-like receptors in the intestinal epithelial cells By Jamshed Arslan, Pharm. D., PhD. Toll-like receptors (TLRs) are microbe-sensing proteins that act as first responders to danger signals. TLRs help the intestinal epithelial cells (IECs) recognize commensal bacteria ...    Read more.

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