Alpha Actinin 4 Products

Antibodies
Alpha Actinin 4 Antibody (4D1 ...
Alpha Actinin 4 Antibody (4D10)
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Alpha Actinin 4 Antibody
Alpha Actinin 4 Antibody
NBP2-15357
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Alpha Actinin 4 Antibody
Alpha Actinin 4 Antibody
NBP1-89818
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
Alpha Actinin 4 Antibody Pair ...
Alpha Actinin 4 Antibody Pair
H00000081-AP41
Species: Hu
Applications: S-ELISA
Alpha Actinin 4 Antibody Pair ...
Alpha Actinin 4 Antibody Pair
H00000081-AP42
Species: Hu
Applications: S-ELISA
Lysates
Alpha Actinin 4 Overexpressio ...
Alpha Actinin 4 Overexpression Lys...
NBL1-07283
Applications: WB
Alpha Actinin 4 Overexpressio ...
Alpha Actinin 4 Overexpression Lys...
H00000081-T01
Species: Hu
Applications: WB
Proteins
Alpha Actinin 4 Recombinant P ...
Alpha Actinin 4 Recombinant Protein
H00000081-P01
Species: Hu
Applications: WB, ELISA, PA
Alpha Actinin 4 Partial Recom ...
Alpha Actinin 4 Partial Recombinan...
H00000081-Q01
Species: Hu
Applications: WB, ELISA, PA
Alpha Actinin 4 Recombinant P ...
Alpha Actinin 4 Recombinant Protei...
NBP1-89818PEP
Species: Hu
Applications: AC
RNAi
Alpha Actinin 4 RNAi
Alpha Actinin 4 RNAi
H00000081-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 81
Alternate Names
  • alpha-actinin-4
  • FSGS1
  • actinin alpha4 isoform
  • FSGS
  • DKFZp686K23158
  • F-actin cross-linking protein
  • ACTININ-4
  • Non-muscle alpha-actinin 4
  • focal segmental glomerulosclerosis 1
  • actinin, alpha 4

Research Areas for Alpha Actinin 4

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific

PTMs for Alpha Actinin 4

Learn more about PTMs related to Alpha Actinin 4.

Phosphorylation
Cleavage
Dephosphorylation
Glycosylation
Ubiquitination

Bioinformatics Tool for Alpha Actinin 4

Discover related pathways, diseases and genes to Alpha Actinin 4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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