Alpha Actinin 4 Products

Antibodies
Alpha Actinin 4 Antibody (4D1 ...
Alpha Actinin 4 Antibody (4D10)
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Alpha Actinin 4 Antibody (JU2 ...
Alpha Actinin 4 Antibody (JU20-23)
NBP2-75404
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
Alpha Actinin 4 Antibody
Alpha Actinin 4 Antibody
NBP2-15357
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ELISA Kits
Human Alpha Actinin 4 ELISA K ...
Human Alpha Actinin 4 ELISA Kit (C...
NBP2-66421
Species: Hu
Applications: ELISA
Lysates
Alpha Actinin 4 Overexpressio ...
Alpha Actinin 4 Overexpression Lysate
NBL1-07283
Species: Hu
Applications: WB
Proteins
Recombinant Human Alpha Actin ...
Recombinant Human Alpha Actinin 4 ...
H00000081-P01
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human Alpha Actin ...
Recombinant Human Alpha Actinin 4 ...
H00000081-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
Alpha Actinin 4 Recombinant P ...
Alpha Actinin 4 Recombinant Protei...
NBP1-89818PEP
Species: Hu
Applications: AC

Description

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 81
Alternate Names
  • alpha-actinin-4
  • FSGS1
  • actinin alpha4 isoform
  • FSGS
  • DKFZp686K23158
  • F-actin cross-linking protein
  • ACTININ-4
  • Non-muscle alpha-actinin 4
  • focal segmental glomerulosclerosis 1
  • actinin, alpha 4

Research Areas for Alpha Actinin 4

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific

PTMs for Alpha Actinin 4

Learn more about PTMs related to Alpha Actinin 4.

Phosphorylation
Cleavage
Dephosphorylation
Glycosylation
Ubiquitination

Bioinformatics Tool for Alpha Actinin 4

Discover related pathways, diseases and genes to Alpha Actinin 4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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