Species: Hu
Applications: WB, Simple Western, IP
Host: Sheep Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC
Host: Rabbit Monoclonal
Description
The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
Bioinformatics
| Product By Gene ID |
250 |
| Alternate Names |
- Alkaline phosphatase Regan isozyme
- alkaline phosphatase, placental type
- alkaline phosphomonoesterase
- ALP
- ALPI
- EC 3.1.3.1
- glycerophosphatase
- IAP
- Intestinal alkaline phosphatase
- intestinal-type alkaline phosphatase
- PALP
- Placental alkaline phosphatase 1
- PLAP
- PLAP-1
|
![Western Blot Alkaline Phosphatase/ALPP/ALPI Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/ALPP_AF5905_Western_Blot_11077.jpg)
![Simple Western Alkaline Phosphatase/ALPP/ALPI Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Alkaline_Phosphatase_ALPP_ALPI_AF5905_Simple_Western_20500.jpg)
