Aldehyde Dehydrogenase 3-A1/ALDH3A1 Products

Description

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]

Bioinformatics

Entrez	218 Human
Uniprot	AAH04370 Human AAH08892.1 Human NM_000691 Human NP_000682 Human NP_000682.3 Human NP_001128639 Human NP_001128640 Human P30838 Human
Product By Gene ID	218
Alternate Names	aldehyde dehydrogenase 3 family, member A1 Aldehyde dehydrogenase 3 Aldehyde dehydrogenase family 3 member A1 aldehyde dehydrogenase isozyme 3 aldehyde dehydrogenase type III ALDH3aldehyde dehydrogenase, dimeric NADP-preferring ALDHIII EC 1.2.1 EC 1.2.1.5 MGC10406 stomach aldehyde dehydrogenase

Research Areas for Aldehyde Dehydrogenase 3-A1/ALDH3A1

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