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HAF016). A specific band was detected for Aldehyde Dehydrogenase 3-A1/ALDH3A1 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
HAF016) in Milk-free Antibody Diluent (Catalog # 043-524). This experiment was conducted under reducing conditions and using the 12-230kDa separation system. Right: Simple Western electropherogram showing the same Sheep Anti-Human Aldehyde Dehydrogenase 3‑A1/ALDH3A1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6705) tested at 10 µg/ml (blue line) and 50 µg/ml (green line) in the human lung." class="big_lightbox" target="_blank">
NL010) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm and nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank">
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]
![Western Blot Aldehyde Dehydrogenase 3-A1/ALDH3A1 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Aldehyde_Dehydrogenase_3A1_AF6705_Western_Blot_12804.jpg)
![Simple Western Aldehyde Dehydrogenase 3-A1/ALDH3A1 Antibody [Unconjugated]](http://images.novusbio.com/images/af6705_human-aldh3a1-affinity-purified-pab-simple-western-639191255530111995.jpg)
![Immunocytochemistry Aldehyde Dehydrogenase 3-A1/ALDH3A1 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Aldehyde_Dehydrogenase_3A1_AF6705_Immunocytochemistry__Immunofluorescence_19085.jpg)
![Immunohistochemistry Aldehyde Dehydrogenase 3-A1/ALDH3A1 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Aldehyde_Dehydrogenase_3A1_AF6705_Immunohistochemistry_19819.jpg)
