Agrin Products

Antibodies
Agrin Antibody [Unconjugated] ...
Agrin Antibody [Unconjugated]
AF550
Species: Rt
Applications: WB, IHC, ELISA(Cap), Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Agrin Antibody
Agrin Antibody
NBP1-90209
Species: Hu, Mouse
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Agrin Antibody (76805)
Agrin Antibody (76805)
MAB550
Species: Rt
Applications: WB
Host: Mouse Monoclonal
Proteins
Agrin Recombinant Protein Ant ...
Agrin Recombinant Protein Antigen
NBP1-90209PEP
Species: Hu
Applications: AC
RNAi
Agrin RNAi
Agrin RNAi
H00375790-R01
Species: Hu

Description

Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction. Agrin, MuSK and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation. The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin. The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components. This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites; increasing the predicted MW from 200kDa to ~600kDa.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Rat
Product By Gene ID 375790
Alternate Names
  • AGRIN
  • agrin proteoglycan
  • agrin

Pathways for Agrin

View related products by pathway and learn more about each of the pathways below.

Cell Adhesion
Pathogenesis
Localization
Cell Death
Cell Development
Proteolysis
Glycosylation
Innervation
Secretion
Rna Splicing

Research Areas for Agrin

Find related products by research area and learn more about each of the different research areas below.

Extracellular Matrix
Neuroscience

PTMs for Agrin

Learn more about PTMs related to Agrin.

Phosphorylation
Glycosylation

Bioinformatics Tool for Agrin

Discover related pathways, diseases and genes to Agrin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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