Agrin Products

Antibodies
Agrin Antibody [Unconjugated] ...
Agrin Antibody [Unconjugated]
AF550
Species: Rt
Applications: WB, IHC, B/N, ELISA(Cap)
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Agrin Antibody
Agrin Antibody
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Agrin Antibody (AGR 131)
Agrin Antibody (AGR 131)
NB110-11069
Species: Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, MiAr
Host: Mouse Monoclonal
ELISA Kits
Rat Agrin DuoSet ELISA, 15 Pl ...
Rat Agrin DuoSet ELISA, 15 Plate
DY550
Species: Rt
Applications: ELISA
Human Agrin ELISA Kit (Chemil ...
Human Agrin ELISA Kit (Chemilumine...
NBP2-66661
Species: Hu
Applications: ELISA
Rat Agrin ELISA Kit (Colorime ...
Rat Agrin ELISA Kit (Colorimetric)
NBP2-66663
Species: Rt
Applications: ELISA
Proteins
Recombinant Rat Agrin Protein ...
Recombinant Rat Agrin Protein
550-AG
Species: Rt
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human Agrin Prote ...
Recombinant Human Agrin Protein, CF
6624-AG
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human Agrin Prote ...
Recombinant Human Agrin Protein, N...
8909-AG
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  

Description

Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction. Agrin, MuSK and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation. The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin. The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components. This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites; increasing the predicted MW from 200kDa to ~600kDa.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Rat
Product By Gene ID 375790
Alternate Names
  • AGRIN
  • agrin proteoglycan
  • agrin

Pathways for Agrin

View related products by pathway and learn more about each of the pathways below.

Cell Adhesion
Pathogenesis
Localization
Cell Death
Cell Development
Proteolysis
Glycosylation
Innervation
Secretion
Rna Splicing

Research Areas for Agrin

Find related products by research area and learn more about each of the different research areas below.

Extracellular Matrix
Neuroscience

PTMs for Agrin

Learn more about PTMs related to Agrin.

Phosphorylation
Glycosylation

Bioinformatics Tool for Agrin

Discover related pathways, diseases and genes to Agrin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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