WB, DB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-PHost:
Aflatoxin B1 is a naturally occurring mycotoxin produced by two types of mold: Aspergillus flavus and Aspergillus parasiticus. These molds commonly affect grains which are grown under stressful conditions such as drought and also grows on food that is stored in hot and humid conditions.
There are 13 known Aflatoxins produced, with aflatoxin B1 considered as the most toxic. In fact, Aflatoxin B1 is the most potent hepatocellular carcinoma (HCC) causing chemical currently known. Specifically, Aflatoxin B1 is thought to case mutations in the p53 gene which interfere with the gene's critical tumor suppressing functions.
Aflatoxin B1 are useful tools for studying hepatocellular carcinoma formation with wide ranging implications into public health and food saftey.
- Aldoketoreductase 7
Research Areas for Aflatoxin B1
Find related products by research area and learn more about each of the different research areas below.Cancer