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Afadin/AF-6 Products

Antibodies
Afadin/AF-6 Antibody - BSA Fr ...
Afadin/AF-6 Antibody - BSA Free
NBP1-90219
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Afadin/AF-6 Antibody (851204) ...
Afadin/AF-6 Antibody (851204) [Unc...
MAB78291
HAF018). A specific band was detected for Afadin/AF-6 at approximately 200-240 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot Afadin/AF-6 Antibody (851204) [Unconjugated]
NL007) and counterstained with DAPI (blue). Specific staining was localized to plasma membrane. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry Afadin/AF-6 Antibody (851204) [Unconjugated]
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Proteins
Afadin/AF-6 Recombinant Prote ...
Afadin/AF-6 Recombinant Protein An...
NBP1-90220PEP
Species: Hu
Applications: AC
Afadin/AF-6 Recombinant Prote ...
Afadin/AF-6 Recombinant Protein An...
NBP1-90219PEP
Species: Hu
Applications: AC
Afadin/AF-6 Recombinant Prote ...
Afadin/AF-6 Recombinant Protein An...
NBP2-55781PEP
Species: Hu
Applications: AC

Description

AF6/Afadin was identified as part of a fusion with MLL (mixed lineage leukemia) in a t(6;11) genetic translocation. AF6/Afadin is also known as afadin (a splicing variant of AF6/Afadin found at adherins junction). AF6/afadin is an actin filament binding protein that binds to nectin at cadherin-based cell-cell adherens junctions and regulates cell-cell adhesion by mediating Ras signaling.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 4301
Alternate Names
  • AF64
  • afadin
  • FLJ34371
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 4