We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

Afadin/AF-6 Products

Antibodies
Afadin/AF-6 Antibody - BSA Fr ...
Afadin/AF-6 Antibody - BSA Free
NBP1-90219
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Proteins
Afadin/AF-6 Recombinant Prote ...
Afadin/AF-6 Recombinant Protein An...
NBP1-90218PEP
Species: Hu
Applications: AC
Afadin/AF-6 Recombinant Prote ...
Afadin/AF-6 Recombinant Protein An...
NBP1-90219PEP
Species: Hu
Applications: AC
Afadin/AF-6 Recombinant Prote ...
Afadin/AF-6 Recombinant Protein An...
NBP2-55781PEP
Species: Hu
Applications: AC

Description

AF6/Afadin was identified as part of a fusion with MLL (mixed lineage leukemia) in a t(6;11) genetic translocation. AF6/Afadin is also known as afadin (a splicing variant of AF6/Afadin found at adherins junction). AF6/afadin is an actin filament binding protein that binds to nectin at cadherin-based cell-cell adherens junctions and regulates cell-cell adhesion by mediating Ras signaling.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 4301
Alternate Names
  • AF64
  • afadin
  • FLJ34371
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 4