Activin RIB/ALK-4 Products

Antibodies
Activin RIB/ALK-4 Antibody [U ...
Activin RIB/ALK-4 Antibody [Unconj...
AF222
Species: Hu
Applications: WB, B/N, KO
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Activin RIB/ALK-4 Antibody
Activin RIB/ALK-4 Antibody
AF1477
Species: Mu
Applications: WB, IHC, B/N
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
Lysates
Activin RIB/ALK-4 Overexpress ...
Activin RIB/ALK-4 Overexpression L...
NBL1-07295
Species: Hu
Applications: WB
Proteins
Recombinant Mouse Activin RIB ...
Recombinant Mouse Activin RIB/ALK-...
1477-AR
Species: Mu
Applications: Binding Activity
Formulation Catalog # Availability Price  
Recombinant Human Activin RIB ...
Recombinant Human Activin RIB/ALK-...
808-AR
Species: Hu
Applications: Binding Activity
Formulation Catalog # Availability Price  
Activin RIB/ALK-4 Recombinant ...
Activin RIB/ALK-4 Recombinant Prot...
NBP2-39003PEP
Species: Hu
Applications: AC

Description

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with a cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type IB receptor, composed of 11 exons. Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants. The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 91
Alternate Names
  • ActRIB
  • EC 2.7.11
  • EC 2.7.11.30
  • Activin receptor type IB
  • Serine/threonine-protein kinase receptor R2
  • ALK-4
  • Activin receptor-like kinase 4
  • ACVRLK4ACTR-IB
  • SKR2activin receptor type-1B
  • ALK4activin A receptor, type II-like kinase 4
  • ACTRIB
  • activin A receptor, type IB

Research Areas for Activin RIB/ALK-4

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for Activin RIB/ALK-4

Learn more about PTMs related to Activin RIB/ALK-4.

Phosphorylation
Cleavage
Ubiquitination
Biotinylation
Dephosphorylation

Bioinformatics Tool for Activin RIB/ALK-4

Discover related pathways, diseases and genes to Activin RIB/ALK-4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.